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A Course in Writing & Appraising Medical Papers

The book entitled „A Course in Writing & Appraising Medical Papers — Easier when you know the rules” is a comprehensive work which contains information on how to improve the understanding and also the technique in writing and submitting a scientific paper to specialized medical journals. The book represents a written support for an online course Read More ...

Multislice Angio Computed Tomography in the Diagnosis of Cardiovascular Diseases

The book entitled “Multislice Angio Computed Tomography in the Diagnosis of Cardiovascular Diseases” (original title “Angio Computer Tomografia Multislice în Diagnosticul Bolilor Cardiovasculare”) represents a comprehensive overview on different applications of this new imaging method in a large variety of cardiovascular applications. Being illustrated with an impressive number of images from the large own casuistry of Read More ...

The Importance of Three Dimensional Electroanatomical Mapping in Radiofrequency Ablation of Scar Related Atrial Flutter

Significance of Serum Uric Acid in Children with Pulmonary Arterial Hypertension

ABSTRACT Introduction: Pulmonary arterial hypertension (PAH) is a complex disease with poor prognosis. Serum uric acid has been proposed as a potentially non-invasive and objective parameter for prognosis and response to therapy. Objectives: To investigate the potent relationship between serum uric acid levels and functional and echocardiographic parameters in children with PAH. Methods: Serum uric Read More ...

Cardioprotective Effects Induced by Preconditioning with Halogenated Anesthetics

ABSTRACT Background: Numerous studies discuss the protective effects of halogenated anesthetics on myocyte injury induced by the ischemia-reperfusion syndrome of the heart. This mechanism is known as pharmacological preconditioning. Aim of the study: The objective of this study was to identify the effects of two volatile anesthetics frequently used in current clinical practice, Isoflurane and Read More ...

The Functional Significance of Myocardial Bridges Determinated with 3D Polar Mapping Method

Limited Cutaneous Scleroderma- Related Pulmonary Arterial Hypertension – a Case Report

ABSTRACT Background: Pulmonary hypertension (PH), defined by mean pulmonary arterial pressure (PAPm) ≥25 mm Hg, can lead to increasing pulmonary vascular resistance, which eventually results in right ventricle failure. Scleroderma, as an autoimmune connective tissue disease, is associated with PH as a sub-group according to the 2015 ESC/ERS PH classification. Pulmonary arterial hypertension (PAH) associated Read More ...

Radiofrequency Catheter Ablation of Parahisian Accessory Pathway

ABSTRACT Radiofrequency catheter ablation of parahisian accessory pathways in pre-excitation syndrome is a challenging task, due to the extremely high risk of complete atrioventricular block.In this brief report we describe the case of a 32 year-old man presenting a parahisian accessory pathway, who has been successfully treated by radiofrequency ablation. Radiofrequency catheter ablation using low-power radiofrequency Read More ...

Left Pulmonary Artery Agenesis in a Pediatric Patient – Case Report

ABSTRACT Unilateral pulmonary artery agenesis is a rare congenital anomaly, that may develop in isolation, or in association with other congenital ardiovascular anomalies, such as tetralogy of Fallot, septal defects, right-sided aortic arch, or pulmonary atresia. Left-sided pulmonary artery agenesis is less frequent than the right-sided one. Diagnosis of unilateral pulmonary artery agenesis can be Read More ...

Perfusion Computed Tomography for the Assessment of Myocardial Viability — a Case Series

ABSTRACT Myocardial viability plays an important role in preventing the development of left ventricular remodeling following an acute myocardial infarction. A preserved viability in the infarcted area has been demonstrated to be associated with a lower amplitude of the remodeling process, while the extent of the non-viable myocardium is directly correlated with the amplitude of Read More ...

Correlations Between the Contrast Density Gradient along the Coronary Stents and Functional Significance of In-stent Restenosis

ABSTRACT Introduction: Coronary artery disease (CAD) is the leading cause of death worldwide and is associated with a significant socio-economic impact. In many cases, patients are treated with implanted coronary stents that carry a significant risk for reobstruction. The aim of our study was to evaluate the importance of coronary computed tomography angiography (CCTA) in evaluating the significance of Read More ...

Correlations Between Severity of Coronary Lesions and Epicardial Fat Volume in Patients with Coronary Artery Disease – a Multislice CT-based Study

ABSTRACT Background: Epicardial fat has been recently identified as a major player in the development of the atherosclerotic process. Study aim: The aim of this study was to correlate the epicardial fat volume (EFV), determined by Multisclice CT, and the severity of the coronary lesions, expressed by the Coronary Calcium Score (CCS) and Syntax Score Read More ...

Predictors of Left Ventricular Remodeling after Revascularized Acute Myocardial Infarction

ABSTRACT Background: The acute loss of myocardium, following an acute myocardial infarction (AMI) leads to an abrupt increase in the loading conditions that induces a pattern of left ventricular remodeling (LVR). It has been shown that remodeling occurs rapidly and progressively within weeks after the AMI. Study aim: The aim of our study was to Read More ...

Characteristics of Coronary Lesions in Small Vessel Disease Treated with Elective Stenting in Patients with Type 2 Diabetes Mellitus

ABSTRACT Background: The incidence of diabetes mellitus (DM) has suffered a dramatic increase and is a serious worldwide issue. Diabetes causes microvascular and macrovascular complications including coronary artery disease (CAD) that ultimately contributes to a high rate of cardiovascular morbidity and mortality. Study aim: The aim of this study was to assess the factors associated Read More ...

Quality of Life after Coronary Revascularization in Patients with Acute Myocardial Infarction

ABSTRACT Background: The quality of life (QoL) in acute myocardial infarction (MI) patients can be improved using 3 therapeutic methods — surgical, pharmaceutical and physical. Study aim: We sought to assess the QoL in patients following an acute MI, with or without percutanous coronary intervention (PCI). Material and methods: A number of 54 patients with Read More ...

Association Between Severity of Peripheral Artery Disease Angio CT- derived Coronary Syntax Score in Patients with Critical Limb Ischemia

ABSTRACT Introduction: Peripheral artery disease, a frequent consequence of atherosclerosis, is usually associated with concomitant ischaemic coronary artery disease and with a high rate of cardiovascular mortality. Material and methods: The study population consisted of 24 patients, admitted to our clinic with peripheral artery disease, 10 of them with critical limb ischaemia. In all cases, Read More ...

Factors Associated with Development of in Coronary Stent Restenosis — the Results of a Multislice Computed Tomography 1-year Follow-up Study

ABSTRACT Introduction: Percutaneous coronary intervention is the first therapeutic choice in the treatment of symptomatic coronary artery disease and Multi-Slice Computed Tomography Coronary Angiography (MSCT-CA) is a new non-invasive diagnostic tool in the follow-up of these patients. The aim of our study was to evaluate the rate of in-stent restenosis (ISR), to identify the predictive Read More ...

Correlations Between Femoral Intima-media Thickness and Cardiovascular Risk Factors in Patients with Ischemic Heart Disease

ABSTRACT Background: Atherosclerosis has a systemic impact, producing gradual stenoses of the main vessels, and many imaging techniques have been developed in order to detect and quantify the atherosclerotic lesions. Peripheral artery disease has been shown to be associated with the presence of coronary heart disease, at the same time with carotid artery involvement. The Read More ...

Can Erectile Dysfunction Predict Major Cardiovascular Events?

ABSTRACT It is estimated that erectile dysfunction (ED) affects more than 150 million people worldwide and this number is expected to double by the year 2025. Vascular component represents the most important etiological cause of erectile dysfunction. ED shares almost all risk factors, such as hypertension, diabetes mellitus, hyperlipidaemia and smoking, with arteriosclerosis. Moderate to Read More ...

Inflammatory Biomarkers in Chronic Obstructive Pulmonary Disease

ABSTRACT Chronic obstructive lung disease (COPD) is a severe progressive disease associated with high morbidity and mortality. Early diagnosis and correct treatment improve the symptoms, quality of life and survival in COPD. Exacerbations of the disease are acute events that cause worsening of COPD symptoms (dyspnea, cough and/or sputum) and may require modification of stable Read More ...

Infective Endocarditis in Children — New Approach in Antimicrobial Prophylaxis

ABSTRACT Infective endocarditis (IE) is an infection of the endocardium and/or heart valves with the formation of a thrombus and secondary damage of the involved tissue, with significant mortality and severe complications. The prevention of bacterial endocarditis is of great controversy. Antimicrobial prophylaxis is usable in the prevention of endocarditis by killing bacteria before or Read More ...

Basic Guidelines in Writing a Scientific Article

Medicine is a complex multidisciplinary domain, which combines a lot of branches of science such as biology, genetics, biochemistry, physiology etc. Medical science has evolved a lot lately in the field of clinical or therapeutic pharmacology, in patient monitoring and in regard to interventional surgery, mainly due to the intense research carried out in these Read More ...

JIM – a Step Forward

The Journal of Interdisciplinary Medicine (JIM) is a new journal that has been created by a group of European researchers and healthcare specialists, in an attempt to provide the opportunity to share the current expertise and scientific achievements between the members of a large family of researchers and medical practitioners. The publication of scientific results is Read More ...