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Innovation and Discovery

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Correlations between Chronological Ages and Dental Ages on a Group of Children with Down Syndrome

ABSTRACT Background: The number of studies on oral complications in children with Down syndrome is substantial, but they are focused rather on the prevalence of dental caries, periodontal disease, and hypodontia. The relationship between Down syndrome and dental eruption has been rarely approached. The causes of delayed eruption in children with Down syn- drome are Read More ...

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Comparative Measurements of Aortic Diameters Using Transthoracic Echocardiography and Thoracic Computed Tomography Angiography in Neonatal Aortic Coarctation

ABSTRACT Background: Critical aortic coarctation is defined as the severe narrowing of the isthmic aortic lumen, representing a neonatal cardiac emergency, part of the congenital heart diseases with duct-dependent systemic circulation. Aim of the study: To assess the correlation between transthoracic echocardiography and computed tomography angiography (CTA) in the mea- surement of aortic diameters in Read More ...

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Preliminary Assessment of Risk Factors for Tooth Wear

ABSTRACT Background: Epidemiological studies have reported an increasing prevalence of tooth wear, and general dental practitioners see a greater number of patients seeking treatment with worn dentition. Improper oral hygiene, unhealthy habits, occupational hazards, and potentially erosive processed foods seem to play a major role in the non-carious loss of dental hard tissue. The aim Read More ...

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Simultaneous Determination of Carbamazepine and Carbamazepine- 10,11-epoxide in Different Biological Matrices by LC-MS/MS

ABSTRACT An uncomplicated, sensitive liquid chromatography linked to mass spectrometry (LC/MS) for evaluation of carbamazepine and carbamazepine-10,11-epoxide (its metabolite) in human plasma, human saliva, rat plasma, and rabbit plasma was developed. Analyses were conducted on a Zorbax SB-C18, 100 mm × 3 mm ID, 3.5 μm column, at a column temperature of 40 ºC. The Read More ...

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The Detection of Proximal Colon Polyps and Its Importance in Screening Colonoscopy

ABSTRACT Background: Colon polyps are precursors of colorectal cancer (CRC), therefore their endoscopic detection is very important. A shift of in the localization of colorectal polyps toward the proximal colon has been recently observed in Western countries. Aim: The aim of this paper was to establish the most important clinical and endoscopic aspects of right Read More ...

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Actual Dose-Reduction Strategies in Cardiac Computed Tomography

ABSTRACT Computed tomography (CT) in cardiac examination is a powerful imaging tool that has developed rapidly during the last decade and continues to increase its potential by bringing novel technologies. Due to its noninvasive character, cardiac CT became a largely used method in detecting coronary diseases or functional issues at the expense of conventional coronary angiography. The accuracy of Read More ...

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Cardiac Magnetic Resonance and Myocardial Viability: Why Is It so Important?

ABSTRACT For a better assessment of ischemic heart diseases, myocardial viability should be quantified. Current studies underline the importance and the evolution of several techniques and methods used in the evaluation of myocardial viability. Taking into account these considerations, the aim of this manuscript was to present the recent points of view regarding myocardial viability and its clinical significance Read More ...

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Use of Circulating and Cellular miRNAs Expression in Forensic Sciences

ABSTRACT The current practice in the field of forensic medicine imposes the use of modern investigation techniques. The complexity of laboratory investigation methods needed for a final result of the investigation in forensic medicine needed new biomarkers of higher specificity and selectivity. Such biomarkers are the microRNAs (miRNAs), short, non-coding RNAs composed of 19–24 nucleotides. Their characteristics, such as Read More ...

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Intracoronary Shear Stress and CT Characteristics of Vulnerable Coronary Plaques

ABSTRACT Vulnerable coronary plaques are associated with a significant risk for rupture, and the ability to detect their characteristic features is of extreme importance, as timely detection of rupture-prone plaques could lead to the appropriate initiation of adequate therapeutic measures and prevent the evolution to an acute coronary event. The most common features of vulnerability in coronary plaques are Read More ...

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Computer-Aided Diagnosis in Colorectal Cancer: Current Concepts and Future Prospects

ABSTRACT Colorectal cancer is an important health issue, both in terms of the number of people affected and the associated costs. Colonoscopy is an important screening method that has a positive impact on the survival of patients with colorectal cancer. The association of colonoscopy with computer-aided diagnostic tools is currently under researchers’ focus, as various Read More ...

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Magnetic Resonance Imaging in Myocardial Fibrosis Related to Ischemic Events

ABSTRACT Given the higher amount of detail it offers, the use of magnetic resonance (MR) in the field of cardiology has increased, thus leading to a decrease in the use of invasive and irradiating methods for diagnosing various cardiovascular disorders. The only precautions for MR imaging are metallic implants and advanced-stage chronic kidney disease. For Read More ...

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The Role of Coronary Computed Tomography Angiography and Cardiac Magnetic Resonance in STEMI Patients with Normal Coronary Angiography

ABSTRACT Usually, the diagnosis of myocardial infarction based on patient symptoms, electrocardiogram (ECG) changes, and cardiac enzymes, is not a challenge for cardiologists. The correlation between coronary anatomy and the ECG territories that present ischemic changes can help the clinician to estimate which coronary artery presents lesions upon performing a coronary angiogram. In certain situations, Read More ...

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Supralevator Total Pelvic Exenteration Without Colostomy — Case Report

ABSTRACT Background: Pelvic exenteration is an ultra-radical surgical procedure described by Brunschwig in 1948, which attempts to surgically cure patients with recurrent pelvic cancer after radiotherapy. Several variants of pelvic exenteration are described that allow a more limited or extensive resection, depending on the stage of the disease. Case report: We report the case of a 54-year-old woman, who Read More ...

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Multiple Coronary Chamber Microfistulas or Persistent Thebesian Vessels?

ABSTRACT Coronary fistulas are rare, not gender-specific congenital conditions, consisting of communications between the coronary arteries and either another coronary vessel or a cardiac chamber. In contrast to large fistulas, small fistulas, named “minimae cordis veneae” or the Thebesius venous system, are draining into heart chambers and form a vascular network in the cardiac lumen. In this article, we Read More ...

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Acute Thrombotic Coronary Occlusion in a Patient with Coronary Artery Anomaly

ABSTRACT Patients with coronary artery anomalies are more susceptible to develop acute thrombotic coronary occlusions due to the abnormal anatomy of these arteries and the disturbance of the pathophysiological mechanisms that lead to an accelerated atherosclerosis development. The following article presents the case of a 64-year-old female patient diagnosed with anterior ST-segment elevation myocardial infarction. Read More ...

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Management of Microvascular Complications in Secondary Diabetes Associated with Autoimmune Diseases — Case Report

ABSTRACT The association of multiple autoimmune diseases may represent the main focus of physicians treating patients with such pathology presenting no comorbidities of different etiology. However, autoimmune diseases and side effects of drugs may lead to development of silent health-threatening diseases that should be identified promptly. We present the case of an elderly, obese, Caucasian female patient suffering of Read More ...

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Leukemia with Plasma Cells — Case Report

ABSTRACT Plasma cell leukemia (PCL) is one of the most aggressive monoclonal gammopathies, being characterized by the presence of more than 20% of plasma cells in the peripheral blood and an absolute number of these cells of more than 2×109, with different morphology, from young elements to mature cells. The incidence of PCL varies between Read More ...

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Myocardial Infarction Complicated with Ventricular Rupture and Pseudo-Aneurysm Formation

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Spontaneous Coronary Artery Dissection as a Cause of Acute Coronary Syndrome in a Young Male Patient with Multiple Cardiovascular Comorbidities

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Intraoperative Differential Diagnosis: Double Gallbladder or Serous Cyst in the Gallbladder Bed?

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The Whitening Efficiency on Colored Teeth

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