Knuckle Pads – Practical Diagnostic Issues

DOI: 10.1515/jim-2017-0044


Knuckle pads are thickening of the skin over the extensor surface of the proximal interphalan- geal joints. Clinical picture, ultrasound imaging, and histopathological examination of the skin biopsy ascertain the diagnosis. In routine practice, two main differential diagnoses are important: knuckle pads vs. pseudo-knuckle pads and idiopathic vs. non-idiopathic forms of knuckle pads.

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