Childhood Perioral Dermatitis — Challenging Treatment

ABSTRACT Background: Also known as papulopustular dermatitis (chronic form), rosacea-like dermatitis, periorificial dermatitis, or airhostess’ dermatitis, perioral dermatitis is a commonly encountered dermatological disease, especially in adult women and less frequently in children. Its diagnosis and treatment are a challenge especially in small children. Case report: We present the case of a 2-year-old girl referred to the dermatologist for Read More …

Prognosis of Patients with Acute Myeloid Leukemia Regarding the Presence FLT3 Gene Mutation – a Case Report

ABSTRACT Acute myeloid leukemia (AML) is a cancerous disease affecting the myeloid line of the bone marrow cells. FLT3, also known as CD135, is a proto-oncogene, which, if mutated, leads to different types of cancer. The protein it encodes presents tyrosine-kinase activity, and its intratandem mutation, FLT3-ITD, leads to uncontrolled proliferation of myeloblasts and worse Read More …

The Evolution of Intracardiac Hemodynamics Post Autologous Stem Cell Transplant in a Case of Multiple Myeloma Associated with Severe Tricuspid and Mitral Valve Insufficiency

ABSTRACT Stem cells are undifferentiated cells that can divide and become differentiated. Hematopoietic stem cells cannot transform into new stem cells such as cardiomyocytes or new heart valves, but they act through paracrine effects, by secreting cytokines and growth factors that lead to an increase in contractility and overall improved function. In this case report, Read More …

Chalk-induced Lung Fibrosis — Case Report

ABSTRACT Introduction: Our article underlines the importance of a good professional anamnesis, knowing all the chemical components with which the patient had been exposed to during her active life as a teacher. Case presentation: A 64-year-old female patient, teacher for 27 years, who had been retired for six years, presented cough with white phlegm and shortness of breath Read More …

Effectiveness of Bronchoalveolar Lavage in Diagnosis and Evolution of Coal Worker’s Pneumoconiosis — Case Report

ABSTRACT Introduction: Our article offers a deeper insight into an important occupational disease — coal workers’ pneumoconiosis, with all its diagnosis difficulties, treatment steps, and strategies. Case presentation: A 33-year-old male patient, smoker, with 16 years of outside exposure to coal dust, presents shortness of breath and cough, which existed 4 months prior to presentation Read More …

Oral Epithelioid Hemangioendothelioma — Unusual Location of a Rare Entity

ABSTRACT Introduction: Epithelioid hemangioendothelioma is a rare, locally aggressive vascular tumor, originating from soft tissue, bone, skin, and organs such as the liver or lung, exceptionally located in the oral cavity. Most of the cases of oral epithelioid hemangioendothelioma are asymptomatic, and diagnosis is hampered by the fact that the histological features are somewhat between Read More …

Atypical Case of Pityriasis Rosea in a Child Following Streptococcal Erythema Nodosum

Introduction: Pityriasis rosea (PR) is a widespread skin erythemato-squamous eruption, occurring mostly in young adults. Case presentation: A 9-year-old patient presented with multiple lesions developed after streptococcal pharyngitis and erythema nodosum diagnosed and treated with penicillin prior to the PR. Conclusion: This unique case should be considered a coincidence of two consecutive diseases.

Biventricular Hypertrophic Cardiomyopathy in a Child with LEOPARD Syndrome: a Case Report

ABSTRACT Background: LEOPARD syndrome is a complex dysmorphogenetic disorder of inconstant penetrance and various morphologic expressions. The syndrome is an autosomal dominant disease that features multiple lentigines, electrocardiographic changes, eye hypertelorism, pulmonary valve stenosis or hypertrophic cardiomyopathy, genital malformations, and a de- layed constitutional growth hearing loss, which can be associated with rapidly progressive se- Read More …

Supralevator Total Pelvic Exenteration Without Colostomy — Case Report

ABSTRACT Background: Pelvic exenteration is an ultra-radical surgical procedure described by Brunschwig in 1948, which attempts to surgically cure patients with recurrent pelvic cancer after radiotherapy. Several variants of pelvic exenteration are described that allow a more limited or extensive resection, depending on the stage of the disease. Case report: We report the case of a 54-year-old woman, who Read More …

Multiple Coronary Chamber Microfistulas or Persistent Thebesian Vessels?

ABSTRACT Coronary fistulas are rare, not gender-specific congenital conditions, consisting of communications between the coronary arteries and either another coronary vessel or a cardiac chamber. In contrast to large fistulas, small fistulas, named “minimae cordis veneae” or the Thebesius venous system, are draining into heart chambers and form a vascular network in the cardiac lumen. In this article, we Read More …