Journal of Interdisciplinary Medicine

A journal of basic and clinical medical research


The Journal of Interdisciplinary Medicine (JIM) has been created by a group of European researchers and healthcare specialists, in an attempt to provide the opportunity to share the current expertise and scientific achievements between the members of a large family of researchers and medical practitioners.

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Current Issue

Volume 2 // Issue 4 // December 2017

Epicardial Fat-mediated Inflammation: a Major Player in Cardiovascular Diseases

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Epicardial Fat, Paracrine-mediated Inflammation and Atrial Fibrillation

ABSTRACT Atrial fibrillation is the most frequent arrhythmia in adults, becoming more frequent with age. Recent clinical studies demonstrated that epicardial fat is linked with atrial fibrillation induction and recurrence. The arrhythmogenic mechanism consists in the fact that the epicardial adipose tissue is metabolically active, inducing local inflammation and enhancing the oxidative stress, which lead to atrial fibrillation as Read More ...

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Anemia and Iron Deficiency in Heart Failure — Clinical Update

ABSTRACT Iron deficiency and anemia affect approximately half of the chronic heart failure patients and they are associated with increased hospitalization rate, lower functional capacity, lower quality of life, and higher mortality. The exact mechanism of iron deficiency in heart failure patients is still not fully understood. Current guidelines recommend ferritin as the most accurate serum biomarker for the Read More ...

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Cardio-renal Correlations and Epicardial Adipose Tissue in Patients with Type 2 Diabetes

ABSTRACT Aim: The aim of the study was to evaluate the correlation between renal function and heart function/echocardiographic parameters and epicardial adipose tissue thickness (EATT), respectively. Material and methods: Fifty patients with type 2 diabetes (T2D) were included in this study. Several laboratory parameters were obtained (HbA1c, fasting blood glucose, LDL-cholesterol, creatinine) and eGFR was calculated. Anthropometric measurements were performed Read More ...

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In-stent Flow Hemodynamics and the Risk of STent Failure Following Bioresorbable Vascular ScAFFolds Implantation – the STAFF Study

ABSTRACT Background: Myocardial revascularization procedures have undergone important developments over the last decades, which led to a major shift in current clinical practice and therapeutic guidelines across the world. Bare metal and drug-eluting stents present several limitations, all centered on the concept of disturbed coronary hemodynamics after implantation, which can be surpassed by bioresorbable vascular scaffolds (BVS). BVSs are Read More ...

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The Usage of the Dental Operating Microscope among Young Dentists in Tîrgu Mureș: A Questionnaire Survey

ABSTRACT Introduction: In the last 15 years, the most important revolution in dentistry has been the introduction and then the widespread adoption of the dental operating microscope. The aim of this study was to evaluate the usage of the dental operating microscope among young specialized and general practitioner dentists in Tîrgu Mureș. Material and Methods: A 9-point questionnaire about Read More ...

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Alveolar Bone Resorption Evaluation Around Single-piece Designed Bicortical Implants, Using Immediate Loading Protocol, Based on Orthopantomographs

ABSTRACT Background: Inserting dental implants in severely atrophied jawbones is a great challenge for the dental practitioner. There are an increasing number of patients who choose dental implantanchored prosthetic restorations despite compromised bone quality and quantity. There have been numerous attempts in adapting implant design for the atrophic crestal bone. One-piece, needle-type basal implant design Read More ...

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Predictive Factors for the Positivity of the Sentinel Lymph Node in Malignant Melanoma

Malignant melanoma is a neoplasia that has its origin in the melanocytes, the melanin-synthesizing pigment cells present in the epidermis or sometimes in the dermis. Sentinel lymph node biopsy (SLNB) is the standard procedure used for staging patients with malignant melanoma in the majority of surgical centers in the world. With a probability of approximately 20% of finding positive Read More ...

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Tinea Incognito — Incorrect Initial Diagnosis. Case Series Presentation with Emphasis on the Mycological Examination

Tinea incognito defines a modified clinical aspect of a tinea following an immunosuppressive therapy, mostly with potent topical steroids. Its diagnosis may be delayed by its delusive appearance, especially in small children and young adults. We present a series of 2 cases of Tinea incognito developed at different ages and incorrectly diagnosed initially, where the clinical diagnosis was followed Read More ...

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Effectiveness of Bronchoalveolar Lavage in Diagnosis and Evolution of Coal Worker’s Pneumoconiosis — Case Report

ABSTRACT Introduction: Our article offers a deeper insight into an important occupational disease — coal workers’ pneumoconiosis, with all its diagnosis difficulties, treatment steps, and strategies. Case presentation: A 33-year-old male patient, smoker, with 16 years of outside exposure to coal dust, presents shortness of breath and cough, which existed 4 months prior to presentation Read More ...

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Biventricular Hypertrophic Cardiomyopathy in a Child with LEOPARD Syndrome: a Case Report

ABSTRACT Background: LEOPARD syndrome is a complex dysmorphogenetic disorder of inconstant penetrance and various morphologic expressions. The syndrome is an autosomal dominant disease that features multiple lentigines, electrocardiographic changes, eye hypertelorism, pulmonary valve stenosis or hypertrophic cardiomyopathy, genital malformations, and a de- layed constitutional growth hearing loss, which can be associated with rapidly progressive se- Read More ...

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Oral Epithelioid Hemangioendothelioma — Unusual Location of a Rare Entity

ABSTRACT Introduction: Epithelioid hemangioendothelioma is a rare, locally aggressive vascular tumor, originating from soft tissue, bone, skin, and organs such as the liver or lung, exceptionally located in the oral cavity. Most of the cases of oral epithelioid hemangioendothelioma are asymptomatic, and diagnosis is hampered by the fact that the histological features are somewhat between Read More ...

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Atypical Case of Pityriasis Rosea in a Child Following Streptococcal Erythema Nodosum

Introduction: Pityriasis rosea (PR) is a widespread skin erythemato-squamous eruption, occurring mostly in young adults. Case presentation: A 9-year-old patient presented with multiple lesions developed after streptococcal pharyngitis and erythema nodosum diagnosed and treated with penicillin prior to the PR. Conclusion: This unique case should be considered a coincidence of two consecutive diseases.

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Chalk-induced Lung Fibrosis — Case Report

ABSTRACT Introduction: Our article underlines the importance of a good professional anamnesis, knowing all the chemical components with which the patient had been exposed to during her active life as a teacher. Case presentation: A 64-year-old female patient, teacher for 27 years, who had been retired for six years, presented cough with white phlegm and shortness of breath Read More ...

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Published Online Ahead of Print

Online Articles

Medical Use of Finite Element Modeling of the Ankle and Foot

ABSTRACT Finite element modeling is a field of medicine with great potential future in experimental studies and in daily clinical practice as well. Computational modeling is currently used in several medical applications including orthopedics, cardiovascular surgery, and dentistry. In orthopedics, this method allows a proper understanding of joint behavior, as well as of more complex articular biomechanics that are Read More ...

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Childhood Perioral Dermatitis — Challenging Treatment

ABSTRACT Background: Also known as papulopustular dermatitis (chronic form), rosacea-like dermatitis, periorificial dermatitis, or airhostess’ dermatitis, perioral dermatitis is a commonly encountered dermatological disease, especially in adult women and less frequently in children. Its diagnosis and treatment are a challenge especially in small children. Case report: We present the case of a 2-year-old girl referred to the dermatologist for Read More ...

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Cutaneous Manifestations of Cystic Fibrosis

ABSTRACT Cystic fibrosis (CF) is an autosomal recessive affliction triggered by genetic mutations in the cystic fibrosis transmembrane conductance regulator. The lung and pancreas are the most frequently affected organs in cystic fibrosis, cutaneous involvement is undervalued and under diagnosed. Skin lesions observed in patients diagnosed with cystic fibrosis are not well known and can create confusions with other Read More ...

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The Efficacy of Questionnaire-based Evaluation in Determining the Incidence of Recent Pseudophakic Dysphotopsia

ABSTRACT Background: Dysphotopsias are optical side effects experienced by patients who underwent cataract surgery. This unwanted photic phenomenon has gained ground and is a major postoperative concern. Visual acuity is not sufficient in evaluating the postoperative visual function. The aim of this study was to determine the efficacy of using a preexistent questionnaire in determining the presence of dysphotopsia. Read More ...

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The Evolution of Silicosis into Massive Pulmonary Fibrosis — Case Series

ABSTRACT Silicosis is one of the oldest occupational diseases, known since the time of Hippocrates, and the diagnosis can be established after a latency time of more than 10 years after exposure cessation. In some cases of chronic silicosis, the disease can progress slowly, evolving over several decades, but it can also evolve into massive pulmonary fibrosis, also Read More ...

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Inflammatory and Imaging-based Predictors of Atrial Fibrillation Recurrence after Pulmonary Vein Isolation Using Electroanatomical Mapping – the INFLAMAP Study

ABSTRACT Atrial fibrillation (AF) is the most frequent form of supraventricular arrhythmia in medical practice. It is characterized by chaotic electrical activity in the atria, which often leads to irregular and fast ventricular contractions. Pulmonary veins (PV) play an essential part in the genesis of AF. There are a series of risk factors that trigger Read More ...

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Prevalence of Chondral Lesions in Knee Arthroscopy

ABSTRACT Background: Chondral and osteochondral injuries of the knee joint are undervalued in subjects undergoing orthopedic surgery. Chondral lesions are difficult to diagnose as they do not present specific clinical signs. The objective of the study was to establish the prevalence of cartilage injuries in patients undergoing arthroscopy of the knee for knee pain or Read More ...

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New Imaging-derived Biomarkers Based on Tridimensional CTA/MRI Hybrid Models for Complex Assessment of Myocardial Viability after Myocardial Infarction – the HYBRIDHEART Study

ABSTRACT Hybrid imaging represents a combination of two different imaging techniques resulting in a single image that contains all the information provided by the two investigations. Hybrid imaging tends to improve the accuracy of the diagnosis in many diseases. Coronary computed tomography angiography (CCTA) has unquestionable abilities in highlighting coronary artery diseases (CAD). Cardiac magnetic Read More ...

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